Mgen Treatment Melbourne

Mycoplasma genitalium treatment is more complex than treatment for chlamydia or gonorrhoea because of significant and increasing antibiotic resistance. According to the Australian STI Management Guidelines, resistance-guided therapy is now the recommended approach — meaning the specific antibiotic prescribed should be determined by testing which drugs the bacteria will respond to before treatment begins. Mgen Treatment Melbourne is available by telehealth from our Specialist GP.

The standard first-line treatment is a two-stage approach. First, a a seven-day course of antibiotics taken twice daily is prescribed as an initial bacterial load reduction step. This is followed by oral antibiotic — either as a single 1g dose or an extended course — if macrolide resistance testing shows the bacteria is susceptible. If macrolide resistance is detected, alternative antibiotics such as alternative antibiotics may be required instead.

Macrolide resistance in Mycoplasma genitalium is a significant and growing concern in Australia, with resistance rates estimated at 40 to 60 per cent in some populations. This high resistance rate is why empirical treatment without resistance testing is discouraged. Your Specialist GP will ensure appropriate resistance testing is performed before selecting the definitive antibiotic, maximising the chance of successful treatment and minimising contribution to further resistance.

A test of cure is essential after Mgen treatment and should be performed three to four weeks after completing the antibiotic course. This differs from chlamydia, where a test of cure at four weeks is recommended but not always mandatory. For Mgen, confirming eradication is important because treatment failure rates are higher and persistent infection can cause ongoing complications including pelvic inflammatory disease and infertility.

All sexual partners should be tested and treated for Mgen. Partner management follows similar principles to chlamydia, but the treatment regimen may need to be individualised based on resistance testing of each partner's infection. Your Specialist GP will advise on partner notification and can coordinate testing and treatment for partners through Clinic365.

All treatment consultations at Clinic365 are conducted by Specialist GPs with extensive experience in sexual health medicine. During your telehealth consultation, your GP will review your test results, confirm the diagnosis, explain the treatment plan, and answer any questions you have. Prescriptions are sent electronically to your nominated pharmacy and can usually be collected the same day. Your GP will also discuss partner notification, safe sex practices during treatment, and when to resume sexual activity.

Follow-up care is an important part of treatment. Depending on the infection, your GP may recommend a test of clearance after completing treatment to confirm the infection has resolved, as well as a repeat screen at three months to check for reinfection. Both follow-up tests can be ordered through Clinic365 for $39 online. If symptoms persist or recur after treatment, your GP is available for reassessment by telehealth. Early detection and prompt treatment remain the most effective way to protect your sexual health and prevent complications.

Telehealth is particularly effective for sexual health consultations because most conditions can be accurately diagnosed from test results and a clinical history alone — a physical examination is rarely needed. This means you can receive the same quality of care from the comfort and privacy of your own home, without needing to take time off work or sit in a waiting room. All Clinic365 telehealth consultations are conducted by Specialist GPs with an interest in sexual health, ensuring you receive expert care regardless of where you are in Australia.